The Cardinals were led by Scottie Eaton who finished with three rushing touchdowns in the game.
Iowa State commit Danny Inglis pitched in two scores as well in the victory.
Matt Jones had a passing and rushing touchdown in a losing effort for the Cowboys.
Get updated high school football scores throughout the season on the WKBN scores page.
Track the latest conference battles on the WKBN high school football standings page.
You can also watch interviews and get player profiles from some of the best players in the Valley by visiting the WKBN Big 22 page.